A visit to an Asklepieion followed a fairly consistent sequence across the many sanctuaries that practiced incubation. Arriving patients first underwent purification, typically bathing and sometimes a preparatory period of dietary restriction, then offered sacrifice and a preliminary payment, before being admitted to the abaton at nightfall to sleep among other supplicants under the sanctuary staff's supervision.
Harmless yellow snakes, sacred to Asklepios and kept within the sanctuary grounds, moved freely through the sleeping hall and were themselves treated as a mode of the god's presence rather than as ordinary animals, a detail that unsettled some visitors and reassured others. During the night the god was hoped to appear directly in a dream, sometimes performing a cure on the spot, described in the inscriptions as touching the affected part, applying a remedy or even conducting a symbolic surgical operation, and sometimes instead prescribing a course of treatment, a diet, an exercise or a medicine, to be carried out by the patient after waking. Either outcome was recorded as a successful cure if the patient's condition subsequently improved. Patients unable to travel could sometimes send a representative to sleep and dream on their behalf, a practice attested in a handful of inscriptions and one further sign that incubation was administered as a flexible therapeutic system rather than a rigid, one size ceremony.