Adrien Adolphe Desbarrolles was born in 1801. He trained and worked as a painter before turning his attention, from around the 1840s onward, to the study of the hand as a serious independent pursuit, drawing on older chiromantic manuscripts and folk tradition alongside his own observation. His major work, Les Mysteres de la Main, first published in 1859 and expanded across several later editions, set out a detailed reading of the lines, mounts and markings of the palm, richly illustrated in a way that made the material accessible well beyond the small circle of earlier occult manuscript readers.
Desbarrolles worked in the same Parisian milieu as Casimir Stanislas d'Arpentigny, whose 1839 Chirognomonie had already established the shape based branch of the field, and the two are remembered as complementary founders rather than rivals: d'Arpentigny gave the practice its study of overall hand form, Desbarrolles its study of the lines. Desbarrolles died in 1886, by which point his books had already become the standard reference nearly every subsequent European and, through translation, English language palmistry manual drew on directly.
Desbarrolles worked without formal patronage for much of his career, supporting himself through his paintings while his hand-reading practice grew by reputation and word of mouth among Parisian society. His later editions of Les Mysteres de la Main grew substantially through repeated revision, incorporating case material and additional plates that made the book increasingly comprehensive with each printing, a working method that mirrors the case-based approach later numerologists such as Juno Jordan would independently apply to their own field decades afterward.